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Breakthrough in Vitamin B5 Biosynthesis Technology

Breakthrough in Vitamin B5 Biosynthesis Technology

Dec 06, 2024

Vitamin B5, an indispensable vitamin for the human body, plays a pivotal role in various sectors such as pharmaceuticals, feed, food, and health supplements. However, traditional methods relying on chemical solvents to extract Vitamin B5 from plants or other natural sources face challenges including high production costs, difficulties in quality control, and unstable supply chains, while also posing potential environmental risks. Therefore, exploring and developing biosynthetic technology for Vitamin B5 is particularly urgent and important.

A Chinese pharmaceutical enterprise has made a breakthrough in this field, successfully developing a biosynthetic manufacturing technology for Vitamin B5 series products. The core of this technology lies in the use of AI models for precise guidance, combined with a series of advanced methods such as high-throughput screening, genome reconstruction, and metabolic network optimization, to deeply optimize the core strains. During this process, the team successfully obtained more efficient key enzyme components and artificial regulatory elements, greatly optimizing the biosynthetic system of D-pantothenic acid and significantly enhancing the technical advantages and market competitiveness of the core strains.

Particularly noteworthy is the technology's achievement of producing D-pantothenic acid through fermentation using renewable biomass carbon sources. This innovation not only broadens the raw material sources and achieves renewability but also demonstrates significant advantages in terms of environmental friendliness and high material and energy utilization rates, opening up a new path for the biosynthetic manufacturing of Vitamin B5 series products. Compared to traditional extraction methods, D-pantothenic acid produced through biological fermentation exhibits remarkable advantages in cost-effectiveness, environmental sustainability, and production efficiency, marking a solid step forward in promoting the green development of the Vitamin B5 industry.

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