Sinoway Industrial Co., Ltd.

Spironolacton 52-01-7 Spironolacton 52-01-7

Spironolacton 52-01-7
Verwandte Produkte
  • L-Glutathion reduziert (GSH) 70-18-8

    L-Glutathion ReducedBasic Informationen von L-Glutathion Reduced: Produktname: L-Glutathion ReducedMolecular Formel: C20H32N6O12S2Molecular Gewicht: 612.63CAS No.:70-18-8ENIECE No: 200-725-4Appearanc ...

  • Kupferpeptid (GHK) 2-CU 49557-75-7

    Kupferpeptid GHK-CuBasische Information des Kupferpeptids GHK-Cu: Produktname (GHK) 2-Cu (Kupferpeptid) SynonymeGHK-Cu (Kupferpeptid) CAS # 49557-75-7MolekularformelC28H46N12O8Cu Molekulargewicht742,2 ...

  • Isoflavone in Soja 574-12-9

    Sojabohnenextrakt1.Basisinformationen von Sojabohnenextrakt: Produktname: SojabohnenextraktQuelle: Glycin maxUsed Teil: Keim / Bohne PulpSpec .: Gesamtsoja Isoflavon 40%, 80% durch HPLCNameSoybean Extract PowderTyp ...

Grundlegende Informationen zu Spironolacton 52-01-7

  • Produktname: Spironolacton
  • Molekülformel: C24H32O4S
  • Molekulargewicht: 416,57
  • CAS-Nr .: 52-01-7
  • Aussehen: Weißes Pulver
  • Spezifikationen: EP8 / USP38

Verwendung von Spironolacton 52-01-7

  • Treat für hohen Blutdruck
  • Treat für primären Hyperaldosteronismus.
  • Treat für Hypokaliämie (Kaliummangel
  • Schweres Herzversagen
  • Ödem (Flüssigkeitsretention) von verschiedenen Zuständen, einschließlich kongestivem Ödem; Leberzirrhose Aszites; Nierenödem
  • Als Kosmetik wirkt Spironolactone im Haarwachstum.

COA von Spironolacton 52-01-7

ITEMS

STANDARDS

RESULTS

Appearance (Ph.Eur.)

A white or yellowish-white powder

White powder

Solubility (Ph.Eur.)

Practically insoluble in water, soluble in ethanol (96%)

Complies

Identification

A. IR–spectrum (Ph.Eur.)

A.  IR–spectrum (USP)

B. TLC (Ph.Eur.)

B.  UV absorption (USP)

C. Colour reaction (Ph.Eur.)

C.  Precipitate reaction (USP)

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Complies

Complies

Complies

Complies

Complies

Complies

Loss on drying

(Ph.Eur.)

(USP)


Not more than 0.5%

Not more than 0.5%


0.24%

0.23%

Specific optical rotation

(Ph.Eur.)

(USP)


-41°~-46°

-41°~-45°


-43.4°

-44.3°

Sulphated ash (Ph.Eur.)

≤0.1%

0.02%

Related substances (Ph.Eur.)

Impurity A

Impurity B

Impurity C

Impurity D

Impurity E

Impurity I

Any unspecified impurity

Total

≤0.2%

≤0.3%

≤0.2%

≤0.15%

≤0.3%

≤0.5%

≤0.10%

≤0.7%

N.D.

N.D.

N.D.

N.D.

N.D.

0.07%

Complies

0.16%

Ordinary impurities (USP)

≤2.0%

Complies

Free thiol compounds (Ph.Eur.)

≤0.05mL

Complies

Free mercapto compounds (USP)

≤0.10mL

Complies

Chromium (Ph.Eur.)

≤50ppm

Complies

Assay

HPLC (Ph.Eur.)

HPLC (USP)


97.5%~102.0%

97.5%~103.0%


100.2%

99.8%

Residual solvent (In-house)

Methanol

Tetrahydrofuran

DMF


≤3000ppm

≤720ppm

≤880ppm


56ppm

≤LOD (0.0046ppm)

≤LOD (0.23ppm)

Particle size (In-house)

95%≤ 20 microns

Complies

Conclusion

Compiles with EP8/USP38


MORE_DETAIL Spironolacton 52-01-7

Grundlegende Informationen zu Spironolacton 52-01-7

  • Produktname: Spironolacton
  • Molekülformel: C24H32O4S
  • Molekulargewicht: 416,57
  • CAS-Nr .: 52-01-7
  • Aussehen: Weißes Pulver
  • Spezifikationen: EP8 / USP38

Verwendung von Spironolacton 52-01-7

  • Treat für hohen Blutdruck
  • Treat für primären Hyperaldosteronismus.
  • Treat für Hypokaliämie (Kaliummangel
  • Schweres Herzversagen
  • Ödem (Flüssigkeitsretention) von verschiedenen Zuständen, einschließlich kongestivem Ödem; Leberzirrhose Aszites; Nierenödem
  • Als Kosmetik wirkt Spironolactone im Haarwachstum.

COA von Spironolacton 52-01-7

ITEMS

STANDARDS

RESULTS

Appearance (Ph.Eur.)

A white or yellowish-white powder

White powder

Solubility (Ph.Eur.)

Practically insoluble in water, soluble in ethanol (96%)

Complies

Identification

A. IR–spectrum (Ph.Eur.)

A.  IR–spectrum (USP)

B. TLC (Ph.Eur.)

B.  UV absorption (USP)

C. Colour reaction (Ph.Eur.)

C.  Precipitate reaction (USP)

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Complies

Complies

Complies

Complies

Complies

Complies

Loss on drying

(Ph.Eur.)

(USP)


Not more than 0.5%

Not more than 0.5%


0.24%

0.23%

Specific optical rotation

(Ph.Eur.)

(USP)


-41°~-46°

-41°~-45°


-43.4°

-44.3°

Sulphated ash (Ph.Eur.)

≤0.1%

0.02%

Related substances (Ph.Eur.)

Impurity A

Impurity B

Impurity C

Impurity D

Impurity E

Impurity I

Any unspecified impurity

Total

≤0.2%

≤0.3%

≤0.2%

≤0.15%

≤0.3%

≤0.5%

≤0.10%

≤0.7%

N.D.

N.D.

N.D.

N.D.

N.D.

0.07%

Complies

0.16%

Ordinary impurities (USP)

≤2.0%

Complies

Free thiol compounds (Ph.Eur.)

≤0.05mL

Complies

Free mercapto compounds (USP)

≤0.10mL

Complies

Chromium (Ph.Eur.)

≤50ppm

Complies

Assay

HPLC (Ph.Eur.)

HPLC (USP)


97.5%~102.0%

97.5%~103.0%


100.2%

99.8%

Residual solvent (In-house)

Methanol

Tetrahydrofuran

DMF


≤3000ppm

≤720ppm

≤880ppm


56ppm

≤LOD (0.0046ppm)

≤LOD (0.23ppm)

Particle size (In-house)

95%≤ 20 microns

Complies

Conclusion

Compiles with EP8/USP38

Verwandte Artikel
Hinterlasse eine Nachricht Email uns

Wir werden uns innerhalb von 24 Stunden bei Ihnen melden.

  • TEL:+ 86-0592-5854962
  • FAX:+ 86-0592-5854960
  • EMAIL: xie@china-sinoway.com
  • ADDRESS:Etage 16, Huicheng Business Center, Nr. 839, Xiahe Rd., Siming Dist. Xiamen, Fujian, China
//